Abstract: From the way that Chinese pharmaceutical supply chains operate currently，the I．eason of the weak eapa— bility of Chinese pharmaceutical enterprise is analyzed profoundly．The conception of kinetic energy of R&D，potential energy of R&D and whole energy of R&D in pharmaceutical enterprise is presented，and the R&D mode based on the core of pharmaceutical enterprises and the whole pharmaceutical supply chain is advanced．Some suggestion and strategy is al— SO given at last．