Abstract: Corporate social responsibility has become the basic expectations, requirements, and constraints of the government, society, and people for enterprise. Meanwhile, that corporate social responsibility is incorporated into the mission, strategy, and culture of company has a significant influence on the enterprise competitiveness. This paper uses social contribution value per share and the annual sales income MoM growth rate respectively to embody the corporate social responsibility level and the enterprise competitiveness. This paper describes that the corporate social responsibility impacts on competitiveness from three aspects that mainly include economy, society, and environment, and uses the system dynamics method to establish the model of the relationship between corporate social responsibility and enterprise competitiveness. It analyzes and forecasts the changes of the enterprise competitiveness under the four kinds of main corporate social behaviors which are respectively paid attention to economic, social, and environmental responsibilities and the balance development of these three kinds of responsibilities. Based on the simulation of Chinese listed companies in the medicine manufacturing industry, the results show that enterprises who focus on implementing a single responsibility are not conducive to promoting enterprise competitiveness and do not implemente corporate social responsibility adequately. Enterprises should function their economic, social, and environmental responsibilities in the process of running so as to keep the rapid advancement of the enterprise competitiveness and realize the sustainable development of enterprises.