Abstract: With the popularization and application of mobile terminals, especially smart phones, various teaching software that based on mobile terminal constantly are being launched, among which " Moso Teach” becomes the leader. This kind of auxiliary teaching software has brought new changes to the traditional teaching model, and its role has gone from behind the scenes to the stage. This paper applies the " Moso Teach” mobile platform to the undergraduate e-commerce professional teaching practice, and combines the mobile Internet with education teaching as an effective teaching tool and means. For further quantitative research on student satisfaction of new teaching methods, we adopt questionnaire survey to the students, and analyze the mobile Internet under the flipped classroom teaching with the traditional teaching methods. The study shows that application of " Moso Teach” mobile platform has a positive role in improving teaching quality and teaching effect, which helps improve the teaching level and class management level, and greatly stimulate the initiative, enthusiasm, and creativity of students learning. This study has a reference value for teaching reform of curriculum in higher education under the background of mobile informationization.