Abstract: Purpose/Significance The objective evaluation of the difference of policies on scientific and technological achievements transformation and the influence of internal factors is of great significance to the continuous improvement of scientific and technological innovation system. Design/Methodology This paper establishes an evaluation model for the policy of scientific and technological achievements transformation. Taking the relevant policies of six provinces and one city in East China between 2011 and 2016 as samples, through policy textual analysis, this paper quantifies the policy differences in three aspects of policy strength, policy comprehensiveness and policy coordination, and introduces the quantitative results into the empirical analysis model. With panel data between 2011 and 2016 in six provinces and one city in East China, regression analysis is conducted for empirical study on the influence of different policies on implementation effects. Findings/Conclusions The research shows that the differences of policy strength, comprehensiveness and coordination of scientific and technological achievements transformation in East China have remarkable influences on the technical and economic output of the policy implementation effect. However, the influence coefficients of the three aspects vary from one another, and there is still room for improvement in policy strength, comprehensiveness, and coordination.