Abstract: As an important part of science and technology finance, bank science and technology loan plays an important role in improving the quality of enterprise innovation. Based on a panel data set, this paper constructs the impact mechanism of bank technology loans on innovation quality, and uses panel regression model and panel threshold model to conduct empirical research on the linear relationship and nonlinear relationship among them. The results show that China’s bank technology loans have a positive impact on the innovation quality. When the level of bank technology loan is low, it has a greater role in promoting the quality of innovation. When the level of enterprise innovation quality is low, the promotion effect of bank technology loans on innovation quality is insufficient. With the level of research and development investment from low to high, the contribution of bank technology loans to innovation quality presents a “U” shape. In order to improve the quality of enterprise innovation, the allocation of research and development funding sources should be optimized.