Abstract: Clearly defining the responsibility of the government in public crisis management is advantageous to scientifically and effectively carrying out the work about the public crisis prevention, response, and the aftermath. Taking "4·11 Lanzhou tap water-benzene bid exceed in 2014 year" for example, this essay attempts to discuss the moral, legal, political, and administrative responsibilities of the government in public crisis management in order to build a relatively systematic government responsibility system in the field. And based on the process optimization, it puts forward some feasible measures which can strengthen the weak links of regulatory measures, information dissemination mechanisms, material reserve systems, and administrative responsibility procedures mechanisms in the public crisis management.