Abstract: The current training pattern for MBA based on the main line of the traditional curriculum must be reformed because the trend of the development of entrepreneurship and innovation, especially the demand characteristics of full-time MBA students. Based on the perspective of innovation, University of Electronic Science and technology of China have explored on it cored with the concept, knowledge and tools which are required in an important stage of the entrepreneurial process. They construct a new full-time MBA training pattern in order to integrate knowledge management and improve innovation ability as the goal including building a course platform design, innovating a curriculum system, and practicing the ability to integrate the training. The new pattern has been named as “Innovation and Transform Leadership Training Program” and operated from 2012. So far, the project has been accepted and supported by the students, enterprises and social.