Abstract: In order to explore the psychological stress among the college staffs in Sichuan province, through a clustered random sampling method, 682 teachers from 7 universities were investigated by a questionnaire. The investigation results are as follows. First, 1.75.9% college staffs have felt severe psychological pressure, 63.7% college staffs feel the psychological stress have already influenced their daily lives, and only 35.3% college staffs feel their pressure coping styles are useful. Second, working problems contribute to the main psychological stressors on college staffs. The psychological stressors influence more on medium qualification group and groups with special difficulties such as divorce or remarry. Third, some college staffs hold incorrect pressure cognitive and the majority college staffs’ stress coping styles are still not perfect. Universities can ease the college staffs’ psychological stress by improving the corresponding policies, popularizing psychological stress knowledge, and constructing organizational cultures