Abstract: Since the “innovation capacity improvement plan for universities and colleges” (abbr. “Plan 211”) has been carried out, lots of national universities have begun to nurture or implement their collaborative innovation one by one. In combination of the practical background and relevant theory, the article describes the content, functions, and basic principles of construction of collaborative innovation platform for universities and colleges. Then the discussion about the platform operation, safeguard mechanism and institutional system construction is carried. Finally, the study may provide some references and suggestions for the progress of collaborative innovation work of our universities and colleges, which is one important part of national innovation system.